The Twilio SendGrid API is a great solution for sending email with CC and BCC fields in Node.js applications. To get started, you need to set up your development environment by installing Node.js and npm, creating a free SendGrid account, and setting up an API key as an environment variable. You then install the SendGrid helper library for Node and create a file called `index.js` with sample code that sends an email with CC and BCC fields using the Twilio SendGrid API. To run this code, you need to set the `SENDGRID_API_KEY` environment variable and replace the email values with your own addresses. Once you've completed these steps, you can successfully send emails with CC and BCC fields in your Node.js application.