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Triggering phone calls in Chrome using Twilio and Zapier allows users to easily connect with their coworkers, cutting through the noise of multiple platforms. The process involves downloading the Zapier Push Chrome Extension, setting up a new push zap, selecting the Twilio account, choosing the phone number to trigger the call, and entering a message to be read aloud by Twilio's voice feature. With this integration, users can quickly alert their team with a coffee break invitation, streamlining communication and increasing productivity. By leveraging the power of code, Zapier and Twilio have created a seamless way to execute calls from within Chrome, making it easy for teams to stay connected and focused throughout the workday.