GitHub Package Registry is a package management service integrated with GitHub, allowing developers to publish packages alongside their source code, but it does not replace JFrog Artifactory or serve as a comprehensive centralized repository like DockerHub or Maven Central. GitHub's service supports six package types and offers a hybrid solution through GitHub Enterprise Server, yet it lacks the extensive features and integrations that Artifactory provides, such as support for 30 package technologies, on-prem and multi-cloud deployment options, and comprehensive third-party tool integrations. Artifactory remains the preferred choice for managing a wide array of packages and ensuring a secure, traceable DevOps pipeline, highlighted by its universal support, robust security features, and flexibility, making it a trusted solution for many global enterprises and tech giants.