This tutorial is designed for individuals with some Python experience who wish to explore decentralized finance (DeFi) without prior knowledge of Solidity or smart contracts. It introduces the concept of DeFi, which offers tools for algorithmic trading with more transparency and flexibility than traditional fintech. A key feature of DeFi is non-custodial lending and borrowing of cryptocurrency assets, allowing for innovative financial activities such as flash loans and yield generation. The tutorial guides users through setting up their environment with tools like Web3.py and Brownie, and covers practical steps to interact with the Aave protocol on Ethereum's Kovan testnet. Users learn to deposit collateral, borrow and repay loans, and manage their cryptocurrency assets using Python scripts. The tutorial emphasizes the advantages of using programming over traditional user interfaces, offering greater creativity and quantitative approaches in DeFi.