Scrapy Splash is an integration of Scrapy, a Python-based web crawling framework, and Splash, a lightweight headless browser used for rendering JavaScript-heavy web pages, aimed at overcoming Scrapy's limitation of handling only static sites. The guide provides a detailed step-by-step tutorial on using Scrapy Splash in Python, describing the setup process, including the use of Docker for running the Splash server and the creation of a Scrapy project with Lua scripts for handling JavaScript rendering. The tutorial further explores advanced scraping techniques such as managing infinite scrolling and implementing waiting logic for dynamic content. Despite its capabilities, Scrapy Splash has limitations like the need for a separate server setup and a less flexible scripting API compared to modern tools like Puppeteer and Playwright. The guide also highlights the challenges posed by anti-scraping technologies and suggests solutions like the Scraping Browser for scalable and resilient web scraping.