The article provides a step-by-step guide on setting up and deploying a Strapi project on a Virtual Private Server (VPS) using Lightsail. Strapi is an open-source headless Content Management System (CMS) that allows for the development of APIs with unique features, built on Node.js and compatible with GraphQL-enabled frontend frameworks. The guide walks through the process of setting up a VPS, installing necessary software such as Git, Yarn, and npm, and configuring the environment using dotenv. It also covers deploying the application using either Forever JS or PM2 to manage the Node.js process. The guide emphasizes ensuring the installation and setup of a reverse proxy like nginx for web port access and concludes with a successful deployment of the Strapi project on the VPS.