WebdriverIO is a highly extensible framework that supports both browser and native mobile app testing, making it suitable for developers who need to test multiple types of apps. Cypress is a popular choice among front-end developers due to its simplicity and ease of setup, but it may not be ideal for full application and browser coverage. TestCafe is an excellent option for desktop or mobile JavaScript apps that are client-side only, while Playwright is a relatively new framework that supports multiple languages and browsers, but still evolving and requires some configuration. Puppeteer is a stable and mature framework suitable for developers who only need to support Chrome and Chromium, with limitations in cross-browser testing. The choice of framework depends on the specific needs of the developer or organization.