Creating an admin panel with GraphQL endpoints using Retool can be accomplished in under 10 minutes, allowing users to perform CRUD operations efficiently without the need for extensive UI development. The process involves building the user interface using Retool's drag-and-drop components, setting up GraphQL queries for the necessary CRUD operations, and linking these queries to the UI components. Users can configure a new app, create tables, and set up necessary queries like `listUsers`, `insertUser`, `updateUser`, and `deleteUser`, which are then integrated with the UI to enable real-time data manipulation. The admin panel utilizes JavaScript expressions to enhance functionality, such as passing data between components and queries, and includes tips for troubleshooting and extending the capabilities of the application. This setup allows for quick testing and iteration, making it accessible for users who may not have extensive programming experience, with additional support available through the Retool community.