When starting a new Python web project, developers often choose between Django, Flask, and FastAPI, each offering distinct advantages based on user preference. Django is a full-featured framework that provides built-in tools such as an ORM, admin UI, and database migrations, appealing to those who prefer an opinionated setup with many features ready to use. In contrast, Flask and FastAPI start with a minimal core, allowing users to make more decisions regarding libraries and extensions, thus appealing to those who prefer simplicity and flexibility. While Flask is a true micro-framework with a vast ecosystem for customization, FastAPI offers built-in features like dependency injection, automatic validation with Pydantic, and interactive API documentation, making it slightly more convenient for certain tasks. Ultimately, the choice depends on whether a developer values a framework with pre-determined options like Django or a simpler starting point with customizable components like Flask and FastAPI, with the latter two sharing many similarities but differing slightly in built-in conveniences.