AI agents, equipped with the capabilities of large language models (LLMs), are increasingly integrated into various systems, from customer support to decision-making pipelines, performing tasks such as querying APIs and modifying infrastructure. However, their autonomy raises concerns regarding trust, as they can make errors like hallucinating actions, misinterpreting prompts, and overstepping boundaries, especially when dealing with sensitive systems. The Human-in-the-Loop (HITL) approach is essential to mitigate these risks by inserting human oversight at critical decision points, thereby combining the efficiency of automation with human judgment. HITL ensures that AI agents act only after receiving explicit human approval, enhancing accountability, compliance, and trust. Various frameworks and libraries, such as LangGraph, CrewAI, HumanLayer, LangChain MCP Adapters, and Permit.io, facilitate HITL integration by providing structured workflows, real-time human approvals, and policy-driven access control. The adoption of HITL is crucial for maintaining control and safety in agentic workflows, ensuring that AI agents remain responsible and within safe operational boundaries.