Using the NiceGUI Python-based Web-UI Framework, the blog post guides readers through building a daily planner application that integrates calendar events and unread emails into a unified interface. The project requires the installation of the NiceGUI package along with the Nylas Python SDK and Dotenv, and involves coding functionalities to retrieve and display the day's events and the latest five unread emails. The application runs a local server displaying the planner's interface, which features a calendar widget allowing users to view events and emails for selected dates. It emphasizes the ease of setup and execution, encouraging users to explore more on Nylas APIs and participate in related live coding sessions.