State management in large frontend applications is a complex challenge, often addressed by using external libraries like Redux and MobX. Redux, which combines Flux and functional programming concepts, is highly popular and features a single store that serves as a single source of truth with immutable states, making it predictable and scalable. However, it has a steep learning curve and requires significant boilerplate code. MobX, on the other hand, offers a more intuitive setup with multiple stores, automatic state tracking, and less boilerplate code, appealing to developers familiar with object-oriented programming. Although both are framework-agnostic and have their strengths, Redux's strong developer community, popularity, and scalability give it an edge over MobX. Nevertheless, MobX is easier to learn and set up, making it suitable for simpler applications.