Modern software development involves a complex software supply chain comprising diverse elements such as open-source packages, commercial software, and infrastructure-as-code files, making it susceptible to various security threats. These threats can be divided into two main paths: exploiting the open nature of the supply chain to gather information for attacks, and injecting malicious code into repositories. Key risks include known vulnerabilities, unknown vulnerabilities (zero-days), non-code issues like misconfigurations, and malicious code. Addressing these risks requires comprehensive security vigilance, integrating analysis tools that span the entire software lifecycle from the development stage to production, to ensure that vulnerabilities are identified and mitigated effectively. Organizations must adopt a holistic security posture, integrating security measures deeply with DevOps tools and maintaining a unified source of truth for all binaries to enable large-scale action against threats.