Real-time monitoring is essential for maintaining the performance and reliability of Django applications, and various tools and techniques can enhance this capability. Custom logging mechanisms using Django's native framework allow developers to capture specific metrics, while Prometheus and Grafana offer a robust solution for metrics collection and visualization. Integrating Prometheus involves setting up metrics such as page views and database query performance, and Grafana provides flexible dashboards for data analysis. Custom middleware in Django can be developed for real-time error tracking, and tools like Hotjar or Crazy Egg provide insights into user interactions through heatmaps and session replays. Additionally, alerting mechanisms such as PagerDuty or OpsGenie ensure that performance anomalies are quickly addressed. By combining these strategies, developers can create a seamless user experience and ensure their Django applications remain highly performant.