Optimizing AI agents by replaying LLM sessions with Helicone offers a method for enhancing their performance by applying modifications to real-world interactions. This approach allows developers to test changes safely without impacting live users, understand the contextual performance of AI agents, and improve user experiences by delivering more accurate interactions. The guide provides a step-by-step process for setting up AI agents with Helicone, retrieving session data, and replaying sessions to analyze the impact of modifications. It emphasizes the use of Helicone's features for evaluations and prompt versioning to refine AI agent responses effectively. By leveraging these tools, developers can achieve better AI outcomes and more robust applications, as Helicone facilitates efficient monitoring and analysis of AI interactions through its open-source LLM observability platform.