End-to-end type safety in JavaScript is crucial for ensuring code correctness and reliability, particularly given the language's dynamically-typed nature. By utilizing tools like TypeScript, developers can introduce static type-checking to catch errors early in the development process, thus improving code maintainability and readability. Setting up a type-safe development environment involves using type-checking tools, adding type-checking to the build process, and enforcing runtime type safety with static type-checkers like TypeScript and runtime tools like prop-types. Best practices include defining interfaces for complex types, using type guards, writing unit tests, and leveraging static analysis tools to catch type errors before they reach production. Advanced strategies such as understanding type systems, using generics, managing dependencies, and building type-safe APIs further enhance type safety. Embracing a culture of type safety involves continuous education, code reviews, and automation to enforce standards, thereby fostering resilient and scalable software development. Additionally, platforms like Split enable controlled feature deployment and experimentation, enhancing development workflows and ensuring features are beneficial without introducing errors.