Company
Date Published
Author
Emily Mosher
Word count
688
Language
-
Hacker News points
None

Summary

Emily Mosher discusses how Daniel Myung and Bhasker Bokuri, scientific computing experts at Merck Pharmaceuticals, are utilizing the Elastic Stack to manage and analyze the vast and complex data generated by the Human Genome Project, aiming to improve the drug discovery process. By leveraging Elastic's capabilities, they can transform raw genomic data into a more manageable, searchable format, which allows researchers to better predict the efficacy of drugs in the early discovery phase, potentially reducing costs and increasing the success rate of new treatments. Despite the initial public expectation that the Human Genome Project would lead to immediate cures for diseases, the reality has been a prolonged process of data analysis and integration. Myung and Bokuri's approach, likened to interpreting weather data, involves harmonizing diverse genomic data sources into a universal coordinate system, enabling faster and more insightful searches that can identify promising drug targets, as illustrated by retrospective insights from the cholesterol drug Lipitor. While the database is still a work in progress, there is hope that incorporating machine learning and statistical methods will further enhance its utility for geneticists, ultimately aiming to raise the pharmaceutical industry's low success rate in developing safe and effective drugs.