Multi-agent orchestration involves the coordination of multiple specialized agents to complete complex tasks, contrasting with single-agent systems where one agent handles all aspects independently. This approach enhances scalability, reliability, and performance by allowing agents to focus on their specific roles while effectively communicating with each other. Orchestration patterns such as the blackboard, orchestrator-worker, and event-driven setups provide structured methodologies for agent interaction, offering clear advantages in terms of speed, cost-efficiency, and accuracy. Various frameworks support these orchestration patterns by managing tasks like scheduling, communication, and monitoring, thus enabling engineers to concentrate on agent development rather than infrastructure complexities. Choosing the right platform is crucial and depends on factors such as scalability, control, and trust, ensuring the system can handle real-world challenges effectively.