Node.js developers often favor NoSQL databases, such as MongoDB and Couchbase, due to their compatibility with JavaScript and JSON. This article explores transitioning applications from MongoDB, using Mongoose as an Object Document Model (ODM), to Couchbase with its ODM, Ottoman, highlighting their similar APIs for ease of migration. The guide outlines building a REST API in Node.js with Mongoose and migrating it to Couchbase, detailing the creation of data models, API endpoints, and server connections for both databases. It emphasizes the flexibility of NoSQL for data modeling, allowing for numerous configurations of student-course relationships, and demonstrates the simplicity of this transition process. The article concludes by underscoring the performance benefits of Couchbase, which integrates caching and scales effectively, making it an appealing option for large-scale applications.