NestJS and Next.js, despite their similar names, serve distinct purposes in web development, with NestJS focusing on backend applications and Next.js supporting frontend-first full-stack development. Built on Node.js, NestJS provides a structured framework suitable for large-scale backend projects, incorporating features such as modular architecture, dependency injection, and integration with databases and GraphQL, making it ideal for enterprise-level applications and microservices. In contrast, Next.js extends React capabilities by offering server-side rendering, static site generation, and API routes, which enhance performance and SEO for web applications. While NestJS is more suited for complex backend logic, Next.js is preferred for building SEO-friendly and performant front-end applications that may incorporate some backend functionalities. Both frameworks can be used together in applications demanding robust backend operations and efficient frontend rendering, such as large e-commerce platforms, where NestJS handles business logic and Next.js manages server-side rendering and dynamic content fetching.