Django's ORM is a key feature that simplifies database interactions, but managing scale and resilience can be challenging with traditional databases like Postgres, SQLite, and MySQL. To address these challenges, CockroachDB has introduced a backend for Django's ORM, combining the simplicity of Python with the advantages of a distributed SQL database. CockroachDB's features, such as automatic sharding, resilience, and high availability, enhance Django applications' scalability and reliability. Users can start using this integration by installing the appropriate version of django-cockroachdb and configuring their Django project settings to connect to CockroachDB, offering a robust solution for developers looking to maintain high-performance applications.