Spot Instances are a cost-effective cloud computing option that allows users to bid on unused capacity from providers like AWS, Azure, and Google Cloud Platform, potentially saving up to 90% off On-Demand pricing. However, they come with the risk of interruptions, as providers can reclaim capacity with little notice, typically between 30 seconds and 2 minutes. Despite this, Spot Instances can still be effectively used for production workloads through automation, which helps manage these interruptions by automatically switching to On-Demand Instances when necessary. They are particularly suitable for stateless and fault-tolerant applications such as batch processing jobs, containers, microservices, high-performance computing, CI/CD operations, and distributed databases. Automation tools, such as Cast AI, enhance the viability of Spot Instances by enabling predictive analytics and real-time responses to interruption notices, as demonstrated by Wio Bank's success in reducing cloud costs. To optimize the use of Spot Instances, users should carefully assess workload requirements, select less popular instance types to minimize interruption risks, set appropriate bidding prices, and manage instances in groups for increased allocation success.